Toltrazuril

EINECS No.

614-893-5 

Molecular formula

C₁₈H₁₄F₃N₃O₄S

Molecular weight

425.38

Molecular structure

Application & advantage

1.Toltrazuril is an antiprotozoal agent that may be considered as an alternative treatment for coccidiosis in dogs and cats, Hepatazoon infections, or for treating the oocyst shedding stage of toxoplasmosis in cats. It has also been used as a treatment for overwhelming parasitic loads in lizards (Bearded Dragons).
2.Toltrazuril has activity against parasites of the genus Hepatozoon, but other drugs (e.g., imidocarb, primaquine, doxycycline) are generally used.
3.While toltrazuril has been used to treat equine protozoal myeloencephalitis (EPM) caused by Sarcocystis neurona, use of approved products now available (e.g., nitazoxanide, ponazuril, pyrimethamine/ sulfadiazine) is preferred.
4.Toltrazuril has been used in some countries to treat Isospora suis in piglets.